Starter Guide
First-time user? Here's everything you need to get started
Register & Log-in
To use Zymscan and all of its features, you’ll first need to create an account.
Registering is easy. Follow the form steps and click “submit”. Once this is done, you’ll receive a link to verify your email.
Remember — You can modify your password, add a profile picture, or edit any other details in your account settings.
Searching on Zymscan
Using ZymScan is simple.
Enter your molecule's name in the “substrate” and “product” fields to see a drop-down list of available options. Select your molecule from each field and press “ZymScan it” to begin the search.
SMILES
( ! ) Available in the Advanced Mode.
Search your substrate and product by its Simplified Molecular Input Line Entry System (SMILES) notation.
— Type in “CCN(CC)CC” to input “Triethylamine”.
Draw your molecule
( ! ) Available in the Advanced Mode.
Use the “Draw your molecule” feature to automatically generate a SMILES notation of your molecule.
There are many ways you can input your reaction:
Natural Language
Search your substrate and product by its ordinary name.
— Type in “Malt sugar” to input “Maltose”, “beta-Maltose” or “D-Maltose”.
CAS Number
Search your substrate and product by its Chemical Abstracts Service number (CAS number).
— Type in “83-67-0” to input “Theobromine”.
Pro Tip — Activate the “Advanced Mode” to unlock all search options
Viewing your results
Once you submit your reaction, ZymScan will screen the available enzyme landscape in search of compatible enzymes.
Results will be classified as “successful” if at least one compatible enzyme family is found for your target reaction.
A successful ZymScan will provide a maximum of 3 different enzyme families that are compatible with your target reaction.
Results provided contain:
Visual representation of enzyme
EC number
Enzyme family
Probability of finding a hit within the suggested family.
Probability of finding a hit is classified as follows:
High probability of finding a hit — There’s a high probability of finding at least one performing enzyme for the target reaction within the suggested enzyme family. The anticipated technical risk associated with the project is low.
Medium probability of finding a hit —There’s a significant probability of finding a performing enzyme for the target reaction within the suggested enzyme family. The anticipated technical risk associated with the project is moderate and might require further analysis.
Low probability of finding a hit — There's a low probability of finding a performing enzyme for the target reaction within the suggested enzyme family. The anticipated technical risk associated with the project is high. Contact Zymvol to get support in exploring alternative strategies.
Viewing your past searches
Need to go back to one of your past searches?
All of your Zymscans are automatically saved in your account.
If you ever need to consult them, you can find them through the “My ZymScans” button, right below the platform’s upper menu.
